Rat Bladder Epithelium: A Sensitive Substrate for Indirect Immunofluorescence of Bullous Pemphigoid: Investigative Report

Localized genital bullous pemphigoid; A case report

Bullous pemphigoid (BP) is an autoimmune bullous disorder with urticarial pruritic papules and plaques and tense bullae in flexural surfaces of body. The localized form of the disease is a rare variant which can be triggered by different stimuli. Hereunder, we report a patient with the local type involving genitalia without any triggering factors.

Methotrexate Induced Bullous Pemphigoid: a Case Report

Background: Bullous pemphigoid (BP) is an autoimmune cutaneous blistering disorder. The precise precipitating etiology is not clear. There has been documented Drug-induced BP in case reports. Case report: We describe a case of a 44year old female with a past medical history of Psoriasis, who developed bullous pemphigoid. She had previously been on maintenance dose of 10mg intravenous methotrexa...

Pathogenic effects of bullous pemphigoid autoantibodies on rabbit corneal epithelium.

Bullous pemphigoid (BP) is associated with circulating autoantibodies reactive with an antigen(s) of the basement membrane zone (BMZ) of skin and mucosae. The pathogenicity of these autoantibodies, although suspected, is unconfirmed. We have investigated the effects of BP autoantibodies on a closely related tissue, the corneal epithelium of the rabbit. IgG fractions from the sera of seven patie...

Analysis of the reactivity of indirect immunofluorescence in patients with pemphigus foliaceus and pemphigus vulgaris using rat bladder epithelium as a substrate

OBJECTIVES To evaluate the reactivity of indirect immunofluorescence using rat bladder epithelium as a substrate in patients with pemphigus foliaceus and pemphigus vulgaris from the Department of Dermatology, University of São Paulo Medical School, Brazil. METHODS Thirty-two patients (8 male and 24 female) from the Department of Dermatology, University of São Paulo Medical School, were select...

Bullous pemphigoid